Protective effects of isohelenin, an inhibitor of nuclear factor kappaB, in endotoxic shock in rats.

Sheehan, M; Wong, H R; Hake, P W; Zingarelli, B

Sheehan, M; Wong, H R; Hake, P W; Zingarelli, B.

Affiliation

Sheehan M; Division of Critical Care Medicine, Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.

J Endotoxin Res ; 8(2): 99-107, 2002.

Article in En | MEDLINE | ID: mdl-12028749

Subject(s)

Endotoxins/toxicity; Lipopolysaccharides/toxicity; NF-kappa B/antagonists & inhibitors; Sesquiterpenes/therapeutic use; Shock, Septic/prevention & control; Acetylcholine/metabolism; Animals; Blotting, Western; Electrophoresis; Hemodynamics/drug effects; Lung/metabolism; Mice; Muscle Contraction/drug effects; Muscle, Smooth, Vascular/drug effects; Nitrates/metabolism; Nitrites/metabolism; Norepinephrine/metabolism; Proteins/metabolism; Rats; Shock, Septic/physiopathology

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Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Aromoterapia Main subject: Sesquiterpenes / Shock, Septic / Lipopolysaccharides / NF-kappa B / Endotoxins Language: En Journal: J Endotoxin Res Year: 2002 Type: Article Affiliation country: United States

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