Diol- and triol-type ginseng saponins potentiate the apoptosis of NIH3T3 cells exposed to methyl methanesulfonate.

Hwang, Sung Jin; Cha, Jae Young; Park, Seh Geun; Joe, Gi Jung; Kim, Hyung Min; Moon, Hyung Bae; Jeong, Se Jin; Lee, Jung Sup; Shin, Dong Hwa; Ko, Sung Ryong; Park, Jong Kun

Hwang, Sung Jin; Cha, Jae Young; Park, Seh Geun; Joe, Gi Jung; Kim, Hyung Min; Moon, Hyung Bae; Jeong, Se Jin; Lee, Jung Sup; Shin, Dong Hwa; Ko, Sung Ryong; Park, Jong Kun.

Affiliation

Hwang SJ; Division of Biological Science, Wonkwang University, Iksan, Chonbuk 570-749, South Korea.

Toxicol Appl Pharmacol ; 181(3): 192-202, 2002 Jun 15.

Article in En | MEDLINE | ID: mdl-12079428

Subject(s)

Apoptosis/drug effects; CDC2-CDC28 Kinases; Methyl Methanesulfonate/toxicity; Mutagens/toxicity; Panax/chemistry; Saponins/pharmacology; 3T3 Cells; Animals; Blotting, Western; Cell Cycle Proteins/metabolism; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases/metabolism; Drug Synergism; Flow Cytometry; Mice; Oligonucleotides, Antisense/pharmacology; Oncogene Protein p21(ras)/metabolism; Protein Serine-Threonine Kinases/metabolism; Saponins/chemistry; Tumor Suppressor Protein p53/metabolism

Search on Google

Add to My VHL

XML

PubMed Links

Database: MEDLINE Main subject: Saponins / Apoptosis / CDC2-CDC28 Kinases / Panax / Methyl Methanesulfonate / Mutagens Language: En Journal: Toxicol Appl Pharmacol Year: 2002 Type: Article Affiliation country: South Korea

Search on Google

Add to My VHL

XML

PubMed Links