Serine/threonine protein kinases synergistically regulate phospholipase D1 and 2 and secretion in RBL-2H3 mast cells.

Chahdi, Ahmed; Choi, Wahn Soo; Kim, Young Mi; Fraundorfer, Paul F; Beaven, Michael A

Chahdi, Ahmed; Choi, Wahn Soo; Kim, Young Mi; Fraundorfer, Paul F; Beaven, Michael A.

Affiliation

Chahdi A; Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institute of Health, Bethesda, MD 20892-1760, USA.

Mol Immunol ; 38(16-18): 1269-76, 2002 Sep.

Article in En | MEDLINE | ID: mdl-12217394

Subject(s)

Mast Cells/enzymology; Phospholipase D/metabolism; Protein Serine-Threonine Kinases/metabolism; Animals; Antigens/immunology; Carbachol/pharmacology; Cholera Toxin/pharmacology; Cyclic AMP-Dependent Protein Kinases/metabolism; Enzyme Inhibitors/pharmacology; Mast Cells/immunology; Mast Cells/metabolism; Phospholipase D/antagonists & inhibitors; Rats; Tetradecanoylphorbol Acetate/pharmacology; Thapsigargin/pharmacology; Tumor Cells, Cultured

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Database: MEDLINE Main subject: Phospholipase D / Protein Serine-Threonine Kinases / Mast Cells Language: En Journal: Mol Immunol Year: 2002 Type: Article Affiliation country: United States

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