Enhanced activity of human IL-10 after nitration in reducing human IL-1 production by stimulated peripheral blood mononuclear cells.

Freels, Jon L; Nelson, Dan K; Hoyt, Jeffrey C; Habib, Michael; Numanami, Hiroki; Lantz, R Clark; Robbins, Richard A

Freels, Jon L; Nelson, Dan K; Hoyt, Jeffrey C; Habib, Michael; Numanami, Hiroki; Lantz, R Clark; Robbins, Richard A.

Affiliation

Freels JL; Research Service, Southern Arizona Veterans Health Care System, Arizona Respiratory Sciences, University of Arizona, 3601 South 6th Avenue, Tucson, AZ 85723, USA.

J Immunol ; 169(8): 4568-71, 2002 Oct 15.

Article in En | MEDLINE | ID: mdl-12370394

Subject(s)

Adjuvants, Immunologic/metabolism; Down-Regulation/immunology; Interleukin-10/metabolism; Interleukin-1/antagonists & inhibitors; Interleukin-1/biosynthesis; Leukocytes, Mononuclear/immunology; Leukocytes, Mononuclear/metabolism; Molsidomine/analogs & derivatives; Peroxynitrous Acid/metabolism; Adjuvants, Immunologic/pharmacology; Anti-Inflammatory Agents, Non-Steroidal/metabolism; Anti-Inflammatory Agents, Non-Steroidal/pharmacology; Cells, Cultured; Deferoxamine/pharmacology; Dithiothreitol/pharmacology; Humans; Hydrogen Peroxide/pharmacology; Interleukin-10/pharmacology; Leukocytes, Mononuclear/drug effects; Molsidomine/pharmacology; Reducing Agents/pharmacology

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Database: MEDLINE Main subject: Molsidomine / Leukocytes, Mononuclear / Down-Regulation / Adjuvants, Immunologic / Interleukin-1 / Interleukin-10 / Peroxynitrous Acid Language: En Journal: J Immunol Year: 2002 Type: Article Affiliation country: United States

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