Mechanistic studies of the effect of hydroxypropyl-beta-cyclodextrin on in vitro transdermal permeation of corticosterone through hairless mouse skin.

Shaker, D S; Ghanem, A-H; Li, S K; Warner, K S; Hashem, F M; Higuchi, W I

Shaker, D S; Ghanem, A-H; Li, S K; Warner, K S; Hashem, F M; Higuchi, W I.

Affiliation

Shaker DS; Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, 30 South 2000 East, 213 Skaggs Hall, Salt Lake City, UT 84112, USA. dalsamuel@hotmail.com

Int J Pharm ; 253(1-2): 1-11, 2003 Mar 06.

Article in En | MEDLINE | ID: mdl-12593932

Subject(s)

Adjuvants, Pharmaceutic/pharmacology; Cellulose/analogs & derivatives; Corticosterone/pharmacokinetics; Cyclodextrins/pharmacology; beta-Cyclodextrins; 2-Hydroxypropyl-beta-cyclodextrin; Adjuvants, Pharmaceutic/chemistry; Administration, Cutaneous; Animals; Biological Transport; Cellulose/chemistry; Corticosterone/chemistry; Cyclodextrins/chemistry; Drug Stability; Female; Hot Temperature; In Vitro Techniques; Membranes, Artificial; Mice; Mice, Hairless; Permeability; Povidone/chemistry; Povidone/pharmacology; Skin Absorption/drug effects; Solubility

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Database: MEDLINE Main subject: Corticosterone / Cellulose / Adjuvants, Pharmaceutic / Cyclodextrins / Beta-Cyclodextrins Language: En Journal: Int J Pharm Year: 2003 Type: Article Affiliation country: United States

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