Erythropoietin restores the anemia-induced reduction in radiosensitivity of experimental human tumors in nude mice.

Stüben, Georg; Pöttgen, Christoph; Knühmann, Kai; Schmidt, Kai; Stuschke, Martin; Thews, Oliver; Vaupel, Peter

Erythropoietin restores the anemia-induced reduction in radiosensitivity of experimental human tumors in nude mice.

Stüben, Georg; Pöttgen, Christoph; Knühmann, Kai; Schmidt, Kai; Stuschke, Martin; Thews, Oliver; Vaupel, Peter.

Affiliation

Stüben G; Department of Radiotherapy, West German Tumor Centre, Universitätsklinikum, Essen, Germany. georg.sueben@uni-essen.de

Int J Radiat Oncol Biol Phys ; 55(5): 1358-62, 2003 Apr 01.

Article in En | MEDLINE | ID: mdl-12654448

Subject(s)

Anemia/drug therapy; Erythropoietin/pharmacology; Radiation Injuries, Experimental/drug therapy; Radiation Tolerance/drug effects; Sarcoma/radiotherapy; Whole-Body Irradiation; Anemia/complications; Anemia/metabolism; Animals; Cell Hypoxia; Dose Fractionation, Radiation; Drug Evaluation, Preclinical; Erythropoietin/therapeutic use; Hemoglobins/analysis; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Radiation Injuries, Experimental/complications; Radiation Injuries, Experimental/metabolism; Recombinant Proteins; Sarcoma/complications; Sarcoma/metabolism; Transplantation, Heterologous; Whole-Body Irradiation/adverse effects

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Database: MEDLINE Main subject: Radiation Injuries, Experimental / Radiation Tolerance / Sarcoma / Whole-Body Irradiation / Erythropoietin / Anemia Language: En Journal: Int J Radiat Oncol Biol Phys Year: 2003 Type: Article Affiliation country: Germany

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