Ascorbate does not act as a pro-oxidant towards lipids and proteins in human plasma exposed to redox-active transition metal ions and hydrogen peroxide.

Suh, Jung; Zhu, Ben-Zhan; Frei, Balz

Suh, Jung; Zhu, Ben-Zhan; Frei, Balz.

Affiliation

Suh J; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331-6512, USA.

Free Radic Biol Med ; 34(10): 1306-14, 2003 May 15.

Article in En | MEDLINE | ID: mdl-12726918

Subject(s)

Antioxidants/pharmacology; Ascorbic Acid/pharmacology; Cholesterol/analogs & derivatives; Copper Sulfate/pharmacology; Ferrous Compounds/pharmacology; Hydrogen Peroxide/pharmacology; Lipid Peroxidation/drug effects; Lipid Peroxides/blood; Quaternary Ammonium Compounds/pharmacology; Ascorbate Oxidase/pharmacology; Cholesterol/metabolism; Humans; Malondialdehyde/blood; Malondialdehyde/metabolism; Oxidation-Reduction; Sulfhydryl Compounds/metabolism; alpha-Tocopherol/blood; alpha-Tocopherol/metabolism

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Database: MEDLINE Main subject: Ascorbic Acid / Ferrous Compounds / Lipid Peroxidation / Cholesterol / Copper Sulfate / Quaternary Ammonium Compounds / Hydrogen Peroxide / Lipid Peroxides / Antioxidants Language: En Journal: Free Radic Biol Med Year: 2003 Type: Article Affiliation country: United States

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