Lack of bioequivalence of levofloxacin when coadministered with a mineral-fortified breakfast of juice and cereal.

Amsden, Guy W; Whitaker, Anne-Marie; Johnson, Patrick W

Amsden, Guy W; Whitaker, Anne-Marie; Johnson, Patrick W.

Affiliation

Amsden GW; Clinical Pharmacology Research Center, Department of Adult and Pediatric Medicine, Bassett Healthcare, One Atwell Road, Cooperstown, NY 13326, USA.

J Clin Pharmacol ; 43(9): 990-5, 2003 Sep.

Article in En | MEDLINE | ID: mdl-12971031

Subject(s)

Anti-Infective Agents/pharmacokinetics; Calcium, Dietary/administration & dosage; Food, Fortified; Food-Drug Interactions; Levofloxacin; Ofloxacin/pharmacokinetics; Adult; Animals; Anti-Infective Agents/administration & dosage; Anti-Infective Agents/blood; Beverages; Citrus; Cross-Over Studies; Edible Grain; Fasting; Female; Humans; Male; Middle Aged; Milk; Ofloxacin/administration & dosage; Ofloxacin/blood; Therapeutic Equivalency

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Database: MEDLINE Main subject: Calcium, Dietary / Ofloxacin / Food, Fortified / Food-Drug Interactions / Levofloxacin / Anti-Infective Agents Type of study: Clinical_trials Language: En Journal: J Clin Pharmacol Year: 2003 Type: Article Affiliation country: United States

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