Potent preventive action of alpha-carotene against carcinogenesis: spontaneous liver carcinogenesis and promoting stage of lung and skin carcinogenesis in mice are suppressed more effectively by alpha-carotene than by beta-carotene.

Murakoshi, M; Nishino, H; Satomi, Y; Takayasu, J; Hasegawa, T; Tokuda, H; Iwashima, A; Okuzumi, J; Okabe, H; Kitano, H

Murakoshi, M; Nishino, H; Satomi, Y; Takayasu, J; Hasegawa, T; Tokuda, H; Iwashima, A; Okuzumi, J; Okabe, H; Kitano, H.

Affiliation

Murakoshi M; Department of Biochemistry, Kyoto Prefectural University of Medicine, Japan.

Cancer Res ; 52(23): 6583-7, 1992 Dec 01.

Article in En | MEDLINE | ID: mdl-1423303

Subject(s)

Carotenoids/therapeutic use; Liver Neoplasms/prevention & control; Lung Neoplasms/prevention & control; Skin Neoplasms/prevention & control; 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms/chemically induced; Male; Mice; Mice, Inbred C3H; Ornithine Decarboxylase/analysis; Papilloma/chemically induced; Papilloma/prevention & control; Skin Neoplasms/chemically induced; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate; beta Carotene

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Database: MEDLINE Main subject: Skin Neoplasms / Carotenoids / Liver Neoplasms / Lung Neoplasms Language: En Journal: Cancer Res Year: 1992 Type: Article Affiliation country: Japan

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