Synthesis and evaluation as sialidase inhibitors of xylo-configured cyclohexenephosphonates carrying glycerol side-chain mimics.

Streicher, Hansjörg

Streicher, Hansjörg.

Affiliation

Streicher H; Department of Chemistry, University of Konstanz, D-78457, Konstanz, Germany. hansjoerg.streicher@uni-konstanz.de

Bioorg Med Chem Lett ; 14(2): 361-4, 2004 Jan 19.

Article in En | MEDLINE | ID: mdl-14698159

Subject(s)

Cyclohexanes/chemical synthesis; Enzyme Inhibitors/chemical synthesis; Glycerol/chemical synthesis; Neuraminidase/antagonists & inhibitors; Clostridium perfringens/drug effects; Clostridium perfringens/enzymology; Clostridium perfringens/growth & development; Cyclohexanes/pharmacology; Cyclohexenes; Drug Evaluation, Preclinical/methods; Enzyme Inhibitors/pharmacology; Glycerol/pharmacology; Neuraminidase/metabolism; Salmonella typhimurium/drug effects; Salmonella typhimurium/enzymology; Salmonella typhimurium/growth & development; Vibrio cholerae/drug effects; Vibrio cholerae/enzymology; Vibrio cholerae/growth & development

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Database: MEDLINE Main subject: Cyclohexanes / Enzyme Inhibitors / Glycerol / Neuraminidase Language: En Journal: Bioorg Med Chem Lett Year: 2004 Type: Article Affiliation country: Germany

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