A turn in the road: How studies on the pharmacology of glucosylceramide synthase inhibitors led to the identification of a lysosomal phospholipase A2 with ceramide transacylase activity.

Shayman, James A; Abe, Akira; Hiraoka, Miki

Shayman, James A; Abe, Akira; Hiraoka, Miki.

Affiliation

Shayman JA; Division of Nephrology, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, MI 48109, USA. jshayman@umich.edu

Glycoconj J ; 20(1): 25-32, 2004.

Article in En | MEDLINE | ID: mdl-14973367

Subject(s)

Acyltransferases/genetics; Acyltransferases/metabolism; Enzyme Inhibitors/pharmacology; Lysosomes/enzymology; Morpholines/pharmacology; Phospholipases A/metabolism; Sphingosine/analogs & derivatives; Acylation; Acyltransferases/isolation & purification; Animals; Cattle; Ceramides/metabolism; DNA, Complementary; Enzyme Inhibitors/chemistry; Glucosyltransferases/antagonists & inhibitors; Humans; Mice; Molecular Structure; Morpholines/chemistry; Phospholipases A2; Signal Transduction; Sphingosine/metabolism

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Database: MEDLINE Main subject: Phospholipases A / Sphingosine / Acyltransferases / Morpholines / Enzyme Inhibitors / Lysosomes Type of study: Diagnostic_studies Language: En Journal: Glycoconj J Year: 2004 Type: Article Affiliation country: United States

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