Characterization of nasal obstruction in the allergic guinea pig using the forced oscillation method.

McLeod, Robbie L; Young, Simon S; Erickson, Christine H; Parra, Leonard E; Hey, John A

McLeod, Robbie L; Young, Simon S; Erickson, Christine H; Parra, Leonard E; Hey, John A.

Affiliation

McLeod RL; Department of Allergy, Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033-0539, USA. robbie.mcleod@spcorp.com

J Pharmacol Toxicol Methods ; 48(3): 153-9, 2002.

Article in En | MEDLINE | ID: mdl-14986864

Subject(s)

Histamine H1 Antagonists/pharmacology; Nasal Decongestants/pharmacology; Nasal Obstruction/drug therapy; Oscillometry/methods; Airway Resistance/drug effects; Animals; Anti-Allergic Agents/therapeutic use; Chlorpheniramine/therapeutic use; Drug Evaluation, Preclinical; Guinea Pigs; Histamine H1 Antagonists/therapeutic use; Male; Nasal Decongestants/therapeutic use; Nasal Obstruction/chemically induced; Nasal Obstruction/physiopathology; Ovalbumin/pharmacology; Pyrilamine/therapeutic use; Time Factors

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Database: MEDLINE Main subject: Oscillometry / Nasal Decongestants / Nasal Obstruction / Histamine H1 Antagonists Type of study: Prognostic_studies Language: En Journal: J Pharmacol Toxicol Methods Year: 2002 Type: Article Affiliation country: United States

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