Novel mechanism of brain soluble epoxide hydrolase-mediated blood pressure regulation in the spontaneously hypertensive rat.

Sellers, Kathleen W; Sun, Chengwen; Diez-Freire, Carlos; Waki, Hidefumi; Morisseau, Christophe; Falck, John R; Hammock, Bruce D; Paton, Julian F; Raizada, Mohan K

Sellers, Kathleen W; Sun, Chengwen; Diez-Freire, Carlos; Waki, Hidefumi; Morisseau, Christophe; Falck, John R; Hammock, Bruce D; Paton, Julian F; Raizada, Mohan K.

Affiliation

Sellers KW; Department of Physiology and Functional Genomics, University of Florida College of Medicine and McKnight Brain Institute, Gainesville, Florida 32610, USA.

FASEB J ; 19(6): 626-8, 2005 Apr.

Article in En | MEDLINE | ID: mdl-15659536

Subject(s)

8,11,14-Eicosatrienoic Acid/analogs & derivatives; Blood Pressure/physiology; Brain/enzymology; Epoxide Hydrolases/metabolism; Homeostasis/physiology; Hypertension/enzymology; 8,11,14-Eicosatrienoic Acid/metabolism; Animals; Baroreflex/physiology; Blotting, Western; Brain Stem/cytology; Cells, Cultured; Epoxide Hydrolases/genetics; Heart Rate; Hypertension/physiopathology; Hypothalamus/cytology; Male; Neurons/physiology; RNA, Messenger/analysis; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species/metabolism; Reverse Transcriptase Polymerase Chain Reaction; Solubility

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Database: MEDLINE Main subject: Blood Pressure / Brain / 8,11,14-Eicosatrienoic Acid / Epoxide Hydrolases / Homeostasis / Hypertension Language: En Journal: FASEB J Year: 2005 Type: Article Affiliation country: United States

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