The antioxidant N-acetylcysteine prevents accelerated atherosclerosis in uremic apolipoprotein E knockout mice.

Ivanovski, Ognen; Szumilak, Dorota; Nguyen-Khoa, Thao; Ruellan, Nadya; Phan, Olivier; Lacour, Bernard; Descamps-Latscha, Béatrice; Drüeke, Tilman B; Massy, Ziad A

Ivanovski, Ognen; Szumilak, Dorota; Nguyen-Khoa, Thao; Ruellan, Nadya; Phan, Olivier; Lacour, Bernard; Descamps-Latscha, Béatrice; Drüeke, Tilman B; Massy, Ziad A.

Affiliation

Ivanovski O; INSERM Unit 507, Necker Hospital, Paris, France. ivanovski@necker.fr

Kidney Int ; 67(6): 2288-94, 2005 Jun.

Article in En | MEDLINE | ID: mdl-15882270

Subject(s)

Acetylcysteine/pharmacology; Antioxidants/pharmacology; Apolipoproteins E/physiology; Arteriosclerosis/prevention & control; Tyrosine/analogs & derivatives; Uremia/complications; Animals; Aorta/pathology; Apolipoproteins E/genetics; Arteriosclerosis/metabolism; Arteriosclerosis/pathology; Body Weight/drug effects; Collagen/analysis; Female; Mice; Mice, Knockout; Tyrosine/analysis

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Database: MEDLINE Main subject: Apolipoproteins E / Arteriosclerosis / Acetylcysteine / Tyrosine / Uremia / Antioxidants Language: En Journal: Kidney Int Year: 2005 Type: Article Affiliation country: France

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