Identification of the microsomal oxidation metabolites of rutaecarpine, a main active alkaloid of the medicinal herb Evodia rutaecarpa.

Ueng, Yune-Fang; Yu, Hsi-Jung; Lee, Chang-Hsin; Peng, Ching; Jan, Woan-Ching; Ho, Li-Kang; Chen, Chieh-Fu; Don, Ming-Jaw

Ueng, Yune-Fang; Yu, Hsi-Jung; Lee, Chang-Hsin; Peng, Ching; Jan, Woan-Ching; Ho, Li-Kang; Chen, Chieh-Fu; Don, Ming-Jaw.

Affiliation

Ueng YF; National Research Institute of Chinese Medicine, 155-1 Li-Nong Street, Sec. 2, Taipei 112, Taiwan, ROC.

J Chromatogr A ; 1076(1-2): 103-9, 2005 May 27.

Article in En | MEDLINE | ID: mdl-15974075

Subject(s)

Alkaloids/metabolism; Evodia/chemistry; Microsomes, Liver/metabolism; Animals; Chromatography, High Pressure Liquid/methods; Indole Alkaloids; Oxidation-Reduction; Quinazolines; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization/methods; Spectrophotometry, Ultraviolet

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Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas Main subject: Microsomes, Liver / Evodia / Alkaloids Type of study: Diagnostic_studies Language: En Journal: J Chromatogr A Year: 2005 Type: Article

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