A HPLC method for the analysis of germacrone in rabbit plasma and its application to a pharmacokinetic study of germacrone after administration of zedoary turmeric oil.

You, Jian; Cui, Fu-de; Li, Qing-po; Yong-sheng, Wang; Han, Xu; Yu, Ying-wei

You, Jian; Cui, Fu-de; Li, Qing-po; Yong-sheng, Wang; Han, Xu; Yu, Ying-wei.

Affiliation

You J; Department of Pharmaceutics, School of Pharmaceutical Science, Shenyang Pharmaceutical University, No. 103 Wenhua Road, Shenyang 110016, China. youjiandoc@yahoo.com.cn

J Chromatogr B Analyt Technol Biomed Life Sci ; 823(2): 172-6, 2005 Sep 05.

Article in En | MEDLINE | ID: mdl-16029964

Subject(s)

Chromatography, High Pressure Liquid/methods; Curcuma/chemistry; Plant Oils/administration & dosage; Sesquiterpenes, Germacrane/blood; Animals; Area Under Curve; Dose-Response Relationship, Drug; Drugs, Chinese Herbal/pharmacokinetics; Injections, Intravenous; Male; Metabolic Clearance Rate; Rabbits; Reproducibility of Results; Sesquiterpenes, Germacrane/pharmacokinetics

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Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Plant Oils / Chromatography, High Pressure Liquid / Curcuma / Sesquiterpenes, Germacrane Type of study: Prognostic_studies Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Year: 2005 Type: Article Affiliation country: China

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