Halothane sensitizes the guinea-pig heart to pharmacological IKr blockade: comparison with urethane anesthesia.

Sakaguchi, Yasue; Sugiyama, Atsushi; Takao, Shuji; Akie, Yasuki; Takahara, Akira; Hashimoto, Keitaro

Sakaguchi, Yasue; Sugiyama, Atsushi; Takao, Shuji; Akie, Yasuki; Takahara, Akira; Hashimoto, Keitaro.

Affiliation

Sakaguchi Y; Department of Pharmacology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Tamaho-cho, Nakakoma-gun, Yamanashi 409-3898, Japan.

J Pharmacol Sci ; 99(2): 185-90, 2005 Oct.

Article in En | MEDLINE | ID: mdl-16217143

Subject(s)

Anesthetics, Inhalation/pharmacology; Anesthetics, Intravenous/pharmacology; Delayed Rectifier Potassium Channels/antagonists & inhibitors; Halothane/pharmacology; Urethane/pharmacology; Action Potentials/drug effects; Anesthetics, Inhalation/administration & dosage; Anesthetics, Intravenous/administration & dosage; Animals; Chromans/pharmacology; Delayed Rectifier Potassium Channels/metabolism; Drug Evaluation, Preclinical; Electrocardiography; Guinea Pigs; Halothane/administration & dosage; Heart Rate/drug effects; Male; Potassium/metabolism; Potassium Channel Blockers/pharmacology; Sotalol/pharmacology; Sulfonamides/pharmacology; Time Factors; Urethane/administration & dosage

Search on Google

Add to My VHL

XML

PubMed Links

Database: MEDLINE Main subject: Urethane / Anesthetics, Intravenous / Anesthetics, Inhalation / Delayed Rectifier Potassium Channels / Halothane Language: En Journal: J Pharmacol Sci Year: 2005 Type: Article Affiliation country: Japan

Search on Google

Add to My VHL

XML

PubMed Links