Analytical studies on the prediction of photosensitive/phototoxic potential of pharmaceutical substances.

Onoue, Satomi; Tsuda, Yoshiko

Onoue, Satomi; Tsuda, Yoshiko.

Affiliation

Onoue S; Analytical Research and Development, Pfizer Global Research and Development, Nagoya Laboratories, Pfizer Japan Inc., 5-2 Taketoyo, Aichi, 470-2393, Japan. satomi.onoue@pfizer.com

Pharm Res ; 23(1): 156-64, 2006 Jan.

Article in En | MEDLINE | ID: mdl-16308671

Subject(s)

Dermatitis, Phototoxic/physiopathology; Drug Evaluation, Preclinical/methods; Drug-Related Side Effects and Adverse Reactions; Photosensitivity Disorders/chemically induced; Algorithms; Chromatography, High Pressure Liquid; Colorimetry; Linoleic Acid/chemistry; Linoleic Acid/radiation effects; Lipid Peroxidation/radiation effects; Quinine/chemistry; Quinine/radiation effects; Reactive Oxygen Species/chemistry; Reactive Oxygen Species/radiation effects; Spectrophotometry, Ultraviolet; Superoxides/chemistry; Superoxides/radiation effects; Thiobarbituric Acid Reactive Substances/chemistry; Ultraviolet Rays

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Database: MEDLINE Main subject: Photosensitivity Disorders / Dermatitis, Phototoxic / Drug Evaluation, Preclinical / Drug-Related Side Effects and Adverse Reactions Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Pharm Res Year: 2006 Type: Article Affiliation country: Japan

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