Role of the extended alpha4 domain of Staphylococcus aureus gyrase A protein in determining low sensitivity to quinolones.

Strahilevitz, Jacob; Robicsek, Ari; Hooper, David C

Strahilevitz, Jacob; Robicsek, Ari; Hooper, David C.

Affiliation

Strahilevitz J; Division of Infectious Diseases, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114-2696, USA.

Antimicrob Agents Chemother ; 50(2): 600-6, 2006 Feb.

Article in En | MEDLINE | ID: mdl-16436716

Subject(s)

Anti-Infective Agents/pharmacology; DNA Gyrase/chemistry; Fluoroquinolones/pharmacology; Staphylococcus aureus/drug effects; Base Sequence; Ciprofloxacin/pharmacology; DNA Gyrase/isolation & purification; Drug Resistance, Bacterial; Escherichia coli/drug effects; Escherichia coli/enzymology; Glutamic Acid/pharmacology; Microbial Sensitivity Tests; Molecular Sequence Data; Protein Structure, Tertiary; Staphylococcus aureus/enzymology; Topoisomerase II Inhibitors

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Full text: 1 Database: MEDLINE Main subject: Staphylococcus aureus / Fluoroquinolones / DNA Gyrase / Anti-Infective Agents Type of study: Diagnostic_studies Language: En Journal: Antimicrob Agents Chemother Year: 2006 Type: Article Affiliation country: United States

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