Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Breast Neoplasms/metabolism; Breast Neoplasms/pathology; Gene Expression Regulation, Neoplastic; Neoplasm Proteins/metabolism; Receptors, Estrogen/metabolism; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols/administration & dosage; Biomarkers, Tumor/metabolism; Breast Neoplasms/drug therapy; Breast Neoplasms/prevention & control; Cisplatin/administration & dosage; Female; Fluorouracil/administration & dosage; Humans; Linear Models; Lymphatic Metastasis; Methotrexate/administration & dosage; Middle Aged; Mitomycins/administration & dosage; Neoplasm Recurrence, Local/metabolism; Neoplasm Recurrence, Local/prevention & control; Odds Ratio; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Reverse Transcriptase Polymerase Chain Reaction; Risk Assessment; Risk Factors; Secondary Prevention; Tamoxifen/administration & dosage