Interaction of neurochondrin with the melanin-concentrating hormone receptor 1 interferes with G protein-coupled signal transduction but not agonist-mediated internalization.

Francke, Felix; Ward, Richard J; Jenkins, Laura; Kellett, Elaine; Richter, Dietmar; Milligan, Graeme; Bächner, Dietmar

Francke, Felix; Ward, Richard J; Jenkins, Laura; Kellett, Elaine; Richter, Dietmar; Milligan, Graeme; Bächner, Dietmar.

Affiliation

Francke F; Institute for Cell Biochemistry and Clinical Neurobiology, University Hospital Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.

J Biol Chem ; 281(43): 32496-507, 2006 Oct 27.

Article in En | MEDLINE | ID: mdl-16945926

Subject(s)

GTP-Binding Proteins/metabolism; Nerve Tissue Proteins/metabolism; Receptors, Pituitary Hormone/metabolism; Signal Transduction; Amino Acid Sequence; Animals; Binding Sites; Biotinylation; COS Cells; Cell Line; Chlorocebus aethiops; DNA, Complementary/metabolism; Escherichia coli/genetics; Humans; Immunohistochemistry; Protein Binding; Rats; Receptors, Pituitary Hormone/chemistry; Receptors, Pituitary Hormone/genetics; Recombinant Fusion Proteins/chemistry; Recombinant Fusion Proteins/metabolism; Transfection

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Database: MEDLINE Main subject: Receptors, Pituitary Hormone / Signal Transduction / GTP-Binding Proteins / Nerve Tissue Proteins Type of study: Prognostic_studies Language: En Journal: J Biol Chem Year: 2006 Type: Article Affiliation country: Germany

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