Risks of human limb deficiency anomalies associated with 29 SNPs of genes involved in homocysteine metabolism, coagulation, cell-cell interactions, inflammatory response, and blood pressure regulation.

Carmichael, Suzan L; Shaw, Gary M; Iovannisci, David M; Yang, Wei; Finnell, Richard H; Cheng, Suzanne; Lammer, Edward J

Carmichael, Suzan L; Shaw, Gary M; Iovannisci, David M; Yang, Wei; Finnell, Richard H; Cheng, Suzanne; Lammer, Edward J.

Affiliation

Carmichael SL; California Birth Defects Monitoring Program, March of Dimes Birth Defects Foundation, Berkeley, California 94710, USA. sca@cbdmp.org

Am J Med Genet A ; 140(22): 2433-40, 2006 Nov 15.

Article in En | MEDLINE | ID: mdl-17036337

Subject(s)

Limb Deformities, Congenital/genetics; Polymorphism, Single Nucleotide; Blood Coagulation/genetics; Blood Pressure/genetics; Case-Control Studies; Cell Communication/genetics; Female; Genotype; Homocysteine/metabolism; Humans; Infant, Newborn; Inflammation/genetics; Limb Deformities, Congenital/etiology; Limb Deformities, Congenital/physiopathology; Male; Maternal-Fetal Exchange; Odds Ratio; Pregnancy; Risk Factors; Smoking/adverse effects; Vitamins/administration & dosage

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Database: MEDLINE Main subject: Limb Deformities, Congenital / Polymorphism, Single Nucleotide Type of study: Etiology_studies / Observational_studies / Risk_factors_studies Language: En Journal: Am J Med Genet A Year: 2006 Type: Article Affiliation country: United States

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