Determination of antibiotic efficacy against Bacillus anthracis in a mouse aerosol challenge model.

Heine, Henry S; Bassett, Jennifer; Miller, Lynda; Hartings, Justin M; Ivins, Bruce E; Pitt, M Louise; Fritz, David; Norris, Sarah L; Byrne, W Russell

Heine, Henry S; Bassett, Jennifer; Miller, Lynda; Hartings, Justin M; Ivins, Bruce E; Pitt, M Louise; Fritz, David; Norris, Sarah L; Byrne, W Russell.

Affiliation

Heine HS; Division of Bacteriology, United States Army Medical Research Institute of Infectious Diseases, 1425 Porter St., Fort Detrick, MD 21702-5011, USA. henry.heine@amedd.army.mil

Antimicrob Agents Chemother ; 51(4): 1373-9, 2007 Apr.

Article in En | MEDLINE | ID: mdl-17296745

Subject(s)

Anthrax/prevention & control; Anti-Bacterial Agents/therapeutic use; Antibiotic Prophylaxis; Ciprofloxacin/therapeutic use; Ofloxacin/therapeutic use; Administration, Inhalation; Aerosols; Animals; Anthrax/immunology; Bacillus anthracis/metabolism; Ciprofloxacin/administration & dosage; Ciprofloxacin/pharmacokinetics; Disease Models, Animal; Mice; Mice, Inbred BALB C; Ofloxacin/administration & dosage; Ofloxacin/pharmacokinetics; Spores, Bacterial/drug effects

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Aromoterapia Main subject: Ofloxacin / Ciprofloxacin / Antibiotic Prophylaxis / Anthrax / Anti-Bacterial Agents Language: En Journal: Antimicrob Agents Chemother Year: 2007 Type: Article Affiliation country: United States

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