Enhancement of hyperthermia-induced apoptosis by a new synthesized class of furan-fused tetracyclic compounds.

Yu, Da-Yong; Matsuya, Yuji; Zhao, Qing-Li; Ahmed, Kanwal; Wei, Zheng-Li; Nemoto, Hideo; Kondo, Takashi

Yu, Da-Yong; Matsuya, Yuji; Zhao, Qing-Li; Ahmed, Kanwal; Wei, Zheng-Li; Nemoto, Hideo; Kondo, Takashi.

Affiliation

Yu DY; Department of Radiological Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Sugitani 2630, Toyama 930-0194, Japan.

Apoptosis ; 12(8): 1523-32, 2007 Aug.

Article in En | MEDLINE | ID: mdl-17458712

Subject(s)

Apoptosis/drug effects; Furans/therapeutic use; Hyperthermia, Induced; Lymphoma, Large B-Cell, Diffuse/therapy; Apoptosis Regulatory Proteins/metabolism; Caspases/metabolism; Combined Modality Therapy; Furans/chemical synthesis; Furans/classification; Heterocyclic Compounds/chemical synthesis; Heterocyclic Compounds/therapeutic use; Humans; Lymphoma, Large B-Cell, Diffuse/pathology; Mitochondria/enzymology; Models, Biological; Reactive Oxygen Species/metabolism; Signal Transduction; U937 Cells; X-Ray Therapy; fas Receptor/metabolism

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Database: MEDLINE Main subject: Lymphoma, Large B-Cell, Diffuse / Apoptosis / Furans / Hyperthermia, Induced Type of study: Evaluation_studies / Prognostic_studies Language: En Journal: Apoptosis Year: 2007 Type: Article Affiliation country: Japan

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