Tetramethylpyrazine inhibits agiontensin II-induced nuclear factor-kappaB activation and bone morphogenetic protein-2 downregulation in rat vascular smooth muscle cells.

Ren, Xin-Yu; Ruan, Qiu-Rong; Zhu, Da-He; Zhu, Min; Qu, Zhi-Ling; Lu, Jun

Ren, Xin-Yu; Ruan, Qiu-Rong; Zhu, Da-He; Zhu, Min; Qu, Zhi-Ling; Lu, Jun.

Affiliation

Ren XY; Department of Pathology, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China.

Sheng Li Xue Bao ; 59(3): 339-44, 2007 Jun 25.

Article in En | MEDLINE | ID: mdl-17579790

Subject(s)

Angiotensin II/antagonists & inhibitors; Atherosclerosis/drug therapy; Bone Morphogenetic Proteins/antagonists & inhibitors; Muscle, Smooth, Vascular/drug effects; Myocytes, Smooth Muscle/metabolism; NF-kappa B/antagonists & inhibitors; Pyrazines/pharmacology; Transforming Growth Factor beta/antagonists & inhibitors; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins/analysis; Immunohistochemistry; Muscle, Smooth, Vascular/cytology; Muscle, Smooth, Vascular/metabolism; NF-kappa B/analysis; Pyrazines/therapeutic use; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta/analysis

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Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Pyrazines / Angiotensin II / NF-kappa B / Transforming Growth Factor beta / Bone Morphogenetic Proteins / Myocytes, Smooth Muscle / Atherosclerosis / Muscle, Smooth, Vascular Type of study: Prognostic_studies Language: En Journal: Sheng Li Xue Bao Year: 2007 Type: Article Affiliation country: China

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