Sesamin, a lignan of sesame, down-regulates cyclin D1 protein expression in human tumor cells.

Yokota, Tomoya; Matsuzaki, Youichirou; Koyama, Makoto; Hitomi, Toshiaki; Kawanaka, Mayumi; Enoki-Konishi, Masako; Okuyama, Yusuke; Takayasu, Junko; Nishino, Hoyoku; Nishikawa, Akiyoshi; Osawa, Toshihiko; Sakai, Toshiyuki

Yokota, Tomoya; Matsuzaki, Youichirou; Koyama, Makoto; Hitomi, Toshiaki; Kawanaka, Mayumi; Enoki-Konishi, Masako; Okuyama, Yusuke; Takayasu, Junko; Nishino, Hoyoku; Nishikawa, Akiyoshi; Osawa, Toshihiko; Sakai, Toshiyuki.

Affiliation

Yokota T; Department of Molecular-Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.

Cancer Sci ; 98(9): 1447-53, 2007 Sep.

Article in En | MEDLINE | ID: mdl-17640297

Subject(s)

Cyclins/antagonists & inhibitors; Cyclins/biosynthesis; Dioxoles/pharmacology; Down-Regulation/drug effects; Lignans/pharmacology; Sesame Oil/pharmacology; Breast Neoplasms/metabolism; Breast Neoplasms/pathology; Cell Line, Transformed; Cell Line, Tumor; Cell Proliferation/drug effects; Cyclin D; Cyclins/genetics; Dioxoles/antagonists & inhibitors; G1 Phase/drug effects; Growth Inhibitors/antagonists & inhibitors; Growth Inhibitors/pharmacology; Humans; Lignans/antagonists & inhibitors; Phosphorylation/drug effects; Protease Inhibitors/pharmacology; Proteasome Endopeptidase Complex/physiology; Proteasome Inhibitors; Proto-Oncogene Mas; Retinoblastoma Protein/antagonists & inhibitors; Retinoblastoma Protein/metabolism

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Database: MEDLINE Main subject: Sesame Oil / Down-Regulation / Cyclins / Lignans / Dioxoles Language: En Journal: Cancer Sci Year: 2007 Type: Article Affiliation country: Japan

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