Red mold rice ameliorates impairment of memory and learning ability in intracerebroventricular amyloid beta-infused rat by repressing amyloid beta accumulation.

Lee, Chun-Lin; Kuo, Tzong-Fu; Wang, Jyh-Jye; Pan, Tzu-Ming

Lee, Chun-Lin; Kuo, Tzong-Fu; Wang, Jyh-Jye; Pan, Tzu-Ming.

Affiliation

Lee CL; Institute of Microbiology and Biochemistry, National Taiwan University, Taipei, Taiwan, Republic of China.

J Neurosci Res ; 85(14): 3171-82, 2007 Nov 01.

Article in En | MEDLINE | ID: mdl-17663476

Subject(s)

Alzheimer Disease/chemically induced; Amyloid beta-Peptides/administration & dosage; Learning/drug effects; Lovastatin/therapeutic use; Memory Disorders/drug therapy; Peptide Fragments/administration & dosage; Phytotherapy/methods; Plant Extracts/therapeutic use; Alzheimer Disease/complications; Analysis of Variance; Animals; Avoidance Learning/drug effects; Behavior, Animal/drug effects; Brain/drug effects; Brain/metabolism; Disease Models, Animal; Drug Interactions; Injections, Intraventricular/methods; Lovastatin/analogs & derivatives; Male; Maze Learning/drug effects; Memory Disorders/etiology; Memory Disorders/pathology; Nerve Tissue Proteins/metabolism; Oryza/chemistry; PC12 Cells/drug effects; Rats; Rats, Wistar

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Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Therapeutic Methods and Therapies TCIM: Terapias_biologicas Main subject: Peptide Fragments / Lovastatin / Plant Extracts / Amyloid beta-Peptides / Alzheimer Disease / Learning / Phytotherapy / Memory Disorders Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Language: En Journal: J Neurosci Res Year: 2007 Type: Article Affiliation country: China

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