IL-10-inducing adjuvants enhance sublingual immunotherapy efficacy in a murine asthma model.

Van Overtvelt, Laurence; Lombardi, Vincent; Razafindratsita, Alain; Saint-Lu, Nathalie; Horiot, Stéphane; Moussu, Hélène; Mascarell, Laurent; Moingeon, Philippe

Van Overtvelt, Laurence; Lombardi, Vincent; Razafindratsita, Alain; Saint-Lu, Nathalie; Horiot, Stéphane; Moussu, Hélène; Mascarell, Laurent; Moingeon, Philippe.

Affiliation

Van Overtvelt L; Research and Development, Stallergènes SA, Antony, France.

Int Arch Allergy Immunol ; 145(2): 152-62, 2008.

Article in En | MEDLINE | ID: mdl-17848808

Subject(s)

Adjuvants, Immunologic/pharmacology; Asthma/therapy; Calcitriol/pharmacology; Dendritic Cells/drug effects; Desensitization, Immunologic; Dexamethasone/pharmacology; Interleukin-10/biosynthesis; Lactobacillus plantarum/immunology; T-Lymphocytes, Regulatory/drug effects; Administration, Sublingual; Animals; Calcitriol/administration & dosage; Cells, Cultured/drug effects; Cells, Cultured/immunology; Dendritic Cells/immunology; Dexamethasone/administration & dosage; Drug Evaluation, Preclinical; Female; Humans; Interleukin-10/genetics; Lacticaseibacillus rhamnosus/immunology; Lymph Nodes/immunology; Mice; Mice, Inbred BALB C; Mice, Transgenic; Ovalbumin/toxicity; T-Lymphocyte Subsets/drug effects; T-Lymphocyte Subsets/immunology; T-Lymphocytes, Regulatory/immunology

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Database: MEDLINE Main subject: Asthma / Dendritic Cells / Calcitriol / Dexamethasone / Adjuvants, Immunologic / Desensitization, Immunologic / Interleukin-10 / T-Lymphocytes, Regulatory / Lactobacillus plantarum Type of study: Prognostic_studies Language: En Journal: Int Arch Allergy Immunol Year: 2008 Type: Article Affiliation country: France

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