Antibody-onconase conjugates: cytotoxicity and intracellular routing.

Rybak, S M

Rybak, S M.

Affiliation

Rybak SM; Bionanomics, LLC, 411 Walnut Street, Green Cove Springs, FL 32043, USA. rybak@mindspring.com

Curr Pharm Biotechnol ; 9(3): 226-30, 2008 Jun.

Article in En | MEDLINE | ID: mdl-18673288

Subject(s)

Antibodies, Monoclonal/therapeutic use; Endocytosis/drug effects; Immunoconjugates/therapeutic use; Neoplasms/drug therapy; Ribonucleases/therapeutic use; ATP Binding Cassette Transporter, Subfamily B, Member 1/immunology; Animals; Antibodies, Monoclonal/administration & dosage; Antibodies, Monoclonal/immunology; Antibodies, Monoclonal/pharmacology; Cell Line, Tumor; Drug Delivery Systems; Humans; Immunoconjugates/administration & dosage; Immunoconjugates/immunology; Immunoconjugates/pharmacology; Microbial Sensitivity Tests; Neoplasms/immunology; Neoplasms/metabolism; Receptors, Transferrin/immunology; Ribonucleases/administration & dosage; Ribonucleases/immunology; Ribonucleases/pharmacology; Sialic Acid Binding Ig-like Lectin 2/immunology

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Database: MEDLINE Therapeutic Methods and Therapies TCIM: Plantas_medicinales Main subject: Ribonucleases / Immunoconjugates / Endocytosis / Antibodies, Monoclonal / Neoplasms Language: En Journal: Curr Pharm Biotechnol Year: 2008 Type: Article Affiliation country: United States

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