Determination of 8-oxo-2'-deoxyguanosine and creatinine in murine and human urine by liquid chromatography/tandem mass spectrometry: application to chemoprevention studies.

Teichert, Friederike; Verschoyle, Richard D; Greaves, Peter; Thorpe, James F; Mellon, J Kilian; Steward, William P; Farmer, Peter B; Gescher, Andreas J; Singh, Rajinder

Teichert, Friederike; Verschoyle, Richard D; Greaves, Peter; Thorpe, James F; Mellon, J Kilian; Steward, William P; Farmer, Peter B; Gescher, Andreas J; Singh, Rajinder.

Affiliation

Teichert F; Cancer Biomarkers and Prevention Group, Department of Cancer Studies and Molecular Medicine, University of Leicester, UK. ft14@leicester.ac.uk

Rapid Commun Mass Spectrom ; 23(2): 258-66, 2009 Jan.

Article in En | MEDLINE | ID: mdl-19072863

Subject(s)

Chromatography, High Pressure Liquid/methods; Creatinine/urine; Deoxyguanosine/analogs & derivatives; Plant Extracts/pharmacokinetics; Prostatic Neoplasms/urine; Spectrometry, Mass, Electrospray Ionization/methods; Tea/chemistry; Urinalysis/methods; 8-Hydroxy-2'-Deoxyguanosine; Adenocarcinoma/urine; Animals; Antineoplastic Agents/administration & dosage; Antineoplastic Agents/pharmacokinetics; Cell Line, Tumor; Deoxyguanosine/urine; Humans; Male; Mice; Mice, Inbred C57BL; Plant Extracts/administration & dosage; Reproducibility of Results; Sensitivity and Specificity

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Full text: 1 Database: MEDLINE Main subject: Prostatic Neoplasms / Tea / Plant Extracts / Chromatography, High Pressure Liquid / Urinalysis / Creatinine / Spectrometry, Mass, Electrospray Ionization / Deoxyguanosine Type of study: Diagnostic_studies / Guideline Language: En Journal: Rapid Commun Mass Spectrom Year: 2009 Type: Article Affiliation country: United kingdom

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