Renoprotective effect of total glucosides of paeony (TGP) and its mechanism in experimental diabetes.

Wu, Yonggui; Ren, Kejun; Liang, Chao; Yuan, Liang; Qi, Xiangming; Dong, Jing; Shen, Jijia; Lin, Shanyan

Wu, Yonggui; Ren, Kejun; Liang, Chao; Yuan, Liang; Qi, Xiangming; Dong, Jing; Shen, Jijia; Lin, Shanyan.

Affiliation

Wu Y; Department of Nephrology, First Affiliated Hospital, Anhui Medical University, Hefei, China. wygxll@ah163.com

J Pharmacol Sci ; 109(1): 78-87, 2009 Jan.

Article in En | MEDLINE | ID: mdl-19151544

Subject(s)

Diabetes Mellitus, Experimental/drug therapy; Glucosides/therapeutic use; Kidney/drug effects; Paeonia/chemistry; Animals; Blood Glucose/metabolism; Body Weight/drug effects; Cholesterol/blood; Collagen Type I/metabolism; Creatinine/blood; Diabetes Mellitus, Experimental/blood; Diabetes Mellitus, Experimental/physiopathology; Dose-Response Relationship, Drug; Glucosides/pharmacology; Intercellular Adhesion Molecule-1/drug effects; Intercellular Adhesion Molecule-1/metabolism; Interleukin-1/biosynthesis; Kidney/metabolism; Kidney/pathology; Male; Membrane Proteins/biosynthesis; Neurotrophin 3/biosynthesis; Phytotherapy; Plant Roots/chemistry; Rats; Rats, Wistar; Transcription Factor RelA/biosynthesis; Transforming Growth Factor beta1/biosynthesis; Triglycerides/blood; Tumor Necrosis Factor-alpha/biosynthesis

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Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Plantas_medicinales Main subject: Paeonia / Diabetes Mellitus, Experimental / Glucosides / Kidney Language: En Journal: J Pharmacol Sci Year: 2009 Type: Article Affiliation country: China

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