Zinc transporter ZIP8 (SLC39A8) and zinc influence IFN-gamma expression in activated human T cells.

Aydemir, Tolunay B; Liuzzi, Juan P; McClellan, Steve; Cousins, Robert J

Aydemir, Tolunay B; Liuzzi, Juan P; McClellan, Steve; Cousins, Robert J.

Affiliation

Aydemir TB; Center for Nutritional Sciences, College of Agricultural and Life Sciences, University of Florida, Gainesville, FL 32611, USA.

J Leukoc Biol ; 86(2): 337-48, 2009 Aug.

Article in En | MEDLINE | ID: mdl-19401385

Subject(s)

Cation Transport Proteins/metabolism; Immunity, Innate/physiology; Interferon-gamma/metabolism; Lymphocyte Activation/immunology; T-Lymphocytes/immunology; Zinc/metabolism; Administration, Oral; Adult; Cation Transport Proteins/genetics; Cells, Cultured; Cyclic AMP Response Element-Binding Protein/metabolism; Dietary Supplements; Down-Regulation/genetics; Down-Regulation/immunology; Enzyme Inhibitors/pharmacology; Humans; Immunity, Innate/drug effects; Lymphocyte Activation/drug effects; Lysosomes/metabolism; Lysosomes/ultrastructure; Male; Perforin/metabolism; Phosphoric Monoester Hydrolases/antagonists & inhibitors; Phosphoric Monoester Hydrolases/metabolism; RNA Interference; T-Lymphocytes/drug effects; Up-Regulation/drug effects; Up-Regulation/immunology; Young Adult; Zinc/pharmacology

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Full text: 1 Database: MEDLINE Main subject: Zinc / Lymphocyte Activation / T-Lymphocytes / Interferon-gamma / Cation Transport Proteins / Immunity, Innate Language: En Journal: J Leukoc Biol Year: 2009 Type: Article Affiliation country: United States

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