Gain-of-function mutations and copy number  increases of Notch2 in diffuse large B-cell lymphoma.

Lee, Suk-young; Kumano, Keiki; Nakazaki, Kumi; Sanada, Masashi; Matsumoto, Akihiko; Yamamoto, Go; Nannya, Yasuhito; Suzuki, Ritsuro; Ota, Satoshi; Ota, Yasunori; Izutsu, Koji; Sakata-Yanagimoto, Mamiko; Hangaishi, Akira; Yagita, Hideo; Fukayama, Masashi; Seto, Masao; Kurokawa, Mineo; Ogawa, Seishi; Chiba, Shigeru

Gain-of-function mutations and copy number increases of Notch2 in diffuse large B-cell lymphoma.

Lee, Suk-young; Kumano, Keiki; Nakazaki, Kumi; Sanada, Masashi; Matsumoto, Akihiko; Yamamoto, Go; Nannya, Yasuhito; Suzuki, Ritsuro; Ota, Satoshi; Ota, Yasunori; Izutsu, Koji; Sakata-Yanagimoto, Mamiko; Hangaishi, Akira; Yagita, Hideo; Fukayama, Masashi; Seto, Masao; Kurokawa, Mineo; Ogawa, Seishi; Chiba, Shigeru.

Affiliation

Lee SY; Department of Cell Therapy and Transplantation Medicine, University of Tokyo Hospital, Tokyo 113-8655, Japan.

Cancer Sci ; 100(5): 920-6, 2009 May.

Article in En | MEDLINE | ID: mdl-19445024

Subject(s)

Gene Dosage/genetics; Lymphoma, Large B-Cell, Diffuse/metabolism; Receptor, Notch2/metabolism; Aged; Aged, 80 and over; Alleles; Base Sequence; DNA, Complementary/genetics; DNA-Binding Proteins/metabolism; Female; Gene Expression Regulation, Neoplastic/genetics; Humans; Interferon Regulatory Factors/metabolism; Lymphoma, Large B-Cell, Diffuse/genetics; Male; Middle Aged; Mutation/genetics; Neprilysin/metabolism; Proto-Oncogene Proteins c-bcl-6; Receptor, Notch2/genetics

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Database: MEDLINE Main subject: Lymphoma, Large B-Cell, Diffuse / Gene Dosage / Receptor, Notch2 Type of study: Prognostic_studies Language: En Journal: Cancer Sci Year: 2009 Type: Article Affiliation country: Japan

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