Hop bitter acids efficiently block inflammation independent of GRalpha, PPARalpha, or PPARgamma.

Van Cleemput, Marjan; Heyerick, Arne; Libert, Claude; Swerts, Katrien; Philippé, Jan; De Keukeleire, Denis; Haegeman, Guy; De Bosscher, Karolien

Van Cleemput, Marjan; Heyerick, Arne; Libert, Claude; Swerts, Katrien; Philippé, Jan; De Keukeleire, Denis; Haegeman, Guy; De Bosscher, Karolien.

Affiliation

Van Cleemput M; Laboratory of Eukaryotic Gene Expression and Signal Transduction (LEGEST), Department of Physiology, Ghent University, Gent, Belgium.

Mol Nutr Food Res ; 53(9): 1143-55, 2009 Sep.

Article in En | MEDLINE | ID: mdl-19655312

Subject(s)

Anti-Inflammatory Agents/pharmacology; Humulus/chemistry; PPAR alpha/physiology; PPAR gamma/physiology; Receptors, Glucocorticoid/physiology; Animals; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein/physiology; Female; Humans; Interleukin-6/biosynthesis; Mice; Mice, Inbred C57BL; NF-kappa B/antagonists & inhibitors; Transcription Factor AP-1/physiology; Transcription, Genetic/drug effects

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Full text: 1 Database: MEDLINE Main subject: Receptors, Glucocorticoid / Humulus / PPAR alpha / PPAR gamma / Anti-Inflammatory Agents Language: En Journal: Mol Nutr Food Res Year: 2009 Type: Article Affiliation country: Belgium

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