Daily brief restraint stress alters signaling pathways and induces atrophy and apoptosis in rat skeletal muscle.

Engelbrecht, Anna-Mart; Smith, Carine; Neethling, Ian; Thomas, Mark; Ellis, Beverly; Mattheyse, Mary; Myburgh, Kathryn H

Engelbrecht, Anna-Mart; Smith, Carine; Neethling, Ian; Thomas, Mark; Ellis, Beverly; Mattheyse, Mary; Myburgh, Kathryn H.

Affiliation

Engelbrecht AM; Department of Physiological Sciences, University of Stellenbosch, Stellenbosch, South Africa. ame@sun.ac.za

Stress ; 13(2): 132-41, 2010 Mar.

Article in En | MEDLINE | ID: mdl-19929313

Subject(s)

Apoptosis; Muscle, Skeletal/pathology; Muscular Atrophy/pathology; Restraint, Physical; Signal Transduction/physiology; Stress, Psychological/physiopathology; Animals; Apoptosis/drug effects; Fabaceae/chemistry; Male; Muscle Proteins/metabolism; Muscle, Skeletal/drug effects; Muscular Atrophy/etiology; MyoD Protein/biosynthesis; Myostatin/biosynthesis; Phosphatidylinositol 3-Kinases/physiology; Plant Extracts/pharmacology; Proto-Oncogene Proteins c-akt/physiology; Rats; Rats, Wistar; SKP Cullin F-Box Protein Ligases/metabolism; Signal Transduction/drug effects; Stress, Psychological/pathology; Tripartite Motif Proteins; Ubiquitin-Protein Ligases/metabolism; p38 Mitogen-Activated Protein Kinases/metabolism

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Full text: 1 Database: MEDLINE Main subject: Stress, Psychological / Restraint, Physical / Muscular Atrophy / Signal Transduction / Apoptosis / Muscle, Skeletal Type of study: Etiology_studies / Prognostic_studies Language: En Journal: Stress Year: 2010 Type: Article Affiliation country: South Africa

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