An LC-MS/MS method for determination of forsythiaside in rat plasma and application to a pharmacokinetic study.

Wang, Geng-Nan; Pan, Rui-Le; Liao, Yong-Hong; Chen, Ying; Tang, Jing-Tian; Chang, Qi

Wang, Geng-Nan; Pan, Rui-Le; Liao, Yong-Hong; Chen, Ying; Tang, Jing-Tian; Chang, Qi.

Affiliation

Wang GN; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 151, Malianwa North Road, Haidian District, Beijing 100193, PR China.

J Chromatogr B Analyt Technol Biomed Life Sci ; 878(1): 102-6, 2010 Jan 01.

Article in En | MEDLINE | ID: mdl-19945919

Subject(s)

Chromatography, Liquid/methods; Glycosides/blood; Tandem Mass Spectrometry/methods; Animals; Area Under Curve; Catechin/analysis; Catechin/chemistry; Catechin/pharmacokinetics; Drug Stability; Drugs, Chinese Herbal/analysis; Drugs, Chinese Herbal/pharmacokinetics; Glycosides/chemistry; Glycosides/pharmacokinetics; Least-Squares Analysis; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction

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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Chromatography, Liquid / Tandem Mass Spectrometry / Glycosides Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Year: 2010 Type: Article

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