[Chemical constituents of Momordica charantia L].
Yao Xue Xue Bao
; 44(9): 1014-8, 2009 Sep.
Article
in Zh
| MEDLINE
| ID: mdl-20055177
ABSTRACT
Momordica charantia L. is a vegetable widely cultivated around the world. Its fruits have been used in Asian countries as a folk medicine for the treatment of non-insulin-dependent diabetes mellitus. Here we report eight compounds isolated from the fruits of M. charantia. On the basis of NMR and MS spectroscopic analyses, these compounds were identified as momordicolide ((10E)-3-hydroxyl-dodeca-10-en-9-olide, 1), monordicophenoide A (4-hydroxyl-benzoic acid 4-O-beta-D-apiofuranosyl (1 --> 2)-O-beta-D-glucopyranoside, 2), dihydrophaseic acid 3-O-beta-D-glucopyranoside (3), 6,9-dihydroxy-megastigman-4,7-dien-3-one (blumenol, 4), guanosine (5), adenosine (6), uracil (7) and cytosine (8). Among them, 1 and 2 are new compounds. Compounds 3-5 were isolated from this plant for the first time.
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Database:
MEDLINE
Main subject:
Momordica charantia
Language:
Zh
Journal:
Yao Xue Xue Bao
Year:
2009
Type:
Article
Affiliation country:
China