Assessment of intestinal absorption of total flavones of Hippophae rhamnoides L. in rat using in situ absorption models.

Xie, Yan; Zeng, Xiaoli; Li, Guowen; Cai, Zhenzhen; Ding, Ning; Ji, Guang

Xie, Yan; Zeng, Xiaoli; Li, Guowen; Cai, Zhenzhen; Ding, Ning; Ji, Guang.

Affiliation

Xie Y; Science and Technology Center, Shanghai University of Traditional Chinese Medicine, Shanghai, PR China.

Drug Dev Ind Pharm ; 36(7): 787-94, 2010 Jul.

Article in En | MEDLINE | ID: mdl-20136488

Subject(s)

Antihypertensive Agents/metabolism; Flavones/pharmacokinetics; Hippophae/chemistry; Hippophae/metabolism; Intestinal Absorption; Intestine, Small/metabolism; ATP Binding Cassette Transporter, Subfamily B, Member 1/antagonists & inhibitors; ATP Binding Cassette Transporter, Subfamily B, Member 1/chemistry; ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism; Absorption; Animals; Antihypertensive Agents/chemistry; Antihypertensive Agents/pharmacokinetics; Antihypertensive Agents/pharmacology; Biological Availability; Drug Stability; Drugs, Chinese Herbal/chemistry; Drugs, Chinese Herbal/pharmacokinetics; Drugs, Chinese Herbal/pharmacology; Flavones/chemistry; Flavones/pharmacology; Intestinal Absorption/drug effects; Male; Polyethylene Glycols/chemistry; Polyethylene Glycols/metabolism; Rats; Rats, Sprague-Dawley; Verapamil/pharmacology

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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Hippophae / Flavones / Intestinal Absorption / Intestine, Small / Antihypertensive Agents Language: En Journal: Drug Dev Ind Pharm Year: 2010 Type: Article

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