Central nociceptin/orphanin FQ system elevates food consumption by both increasing energy intake and reducing aversive responsiveness.

Olszewski, Pawel K; Grace, Martha K; Fard, Shahrzad Shirazi; Le Grevès, Madeleine; Klockars, Anica; Massi, Maurizio; Schiöth, Helgi B; Levine, Allen S

Olszewski, Pawel K; Grace, Martha K; Fard, Shahrzad Shirazi; Le Grevès, Madeleine; Klockars, Anica; Massi, Maurizio; Schiöth, Helgi B; Levine, Allen S.

Affiliation

Olszewski PK; Minnesota Obesity Center, Saint Paul, Minnesota, USA.

Am J Physiol Regul Integr Comp Physiol ; 299(2): R655-63, 2010 Aug.

Article in En | MEDLINE | ID: mdl-20427724

Subject(s)

Behavior, Animal; Brain/metabolism; Conditioning, Psychological; Eating; Energy Intake; Hunger; Opioid Peptides/metabolism; Signal Transduction; Amygdala/metabolism; Animals; Behavior, Animal/drug effects; Brain/drug effects; Brain Stem/metabolism; Conditioning, Psychological/drug effects; Eating/drug effects; Energy Intake/drug effects; Extinction, Psychological; Gene Expression Regulation; Hunger/drug effects; Hypothalamus/metabolism; Immunohistochemistry; Injections, Intraventricular; Lithium Chloride/administration & dosage; Male; Narcotic Antagonists; Opioid Peptides/genetics; Peptide Fragments/administration & dosage; Proto-Oncogene Proteins c-fos/metabolism; RNA, Messenger/metabolism; Rats; Rats, Sprague-Dawley; Receptors, Opioid/metabolism; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction/drug effects; Time Factors; Nociceptin Receptor; Nociceptin

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Full text: 1 Database: MEDLINE Complementary Medicines: Homeopatia Main subject: Behavior, Animal / Brain / Energy Intake / Signal Transduction / Hunger / Opioid Peptides / Conditioning, Psychological / Eating Language: En Journal: Am J Physiol Regul Integr Comp Physiol Year: 2010 Type: Article Affiliation country: United States

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