A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes.

Sun, Dongmei; Zhuang, Xiaoying; Xiang, Xiaoyu; Liu, Yuelong; Zhang, Shuangyin; Liu, Cunren; Barnes, Stephen; Grizzle, William; Miller, Donald; Zhang, Huang-Ge

Sun, Dongmei; Zhuang, Xiaoying; Xiang, Xiaoyu; Liu, Yuelong; Zhang, Shuangyin; Liu, Cunren; Barnes, Stephen; Grizzle, William; Miller, Donald; Zhang, Huang-Ge.

Affiliation

Sun D; Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Mol Ther ; 18(9): 1606-14, 2010 Sep.

Article in En | MEDLINE | ID: mdl-20571541

Subject(s)

Anti-Inflammatory Agents/administration & dosage; Anti-Inflammatory Agents/therapeutic use; Curcumin/administration & dosage; Curcumin/therapeutic use; Exosomes/chemistry; Nanoparticles/therapeutic use; Animals; Anti-Inflammatory Agents/chemistry; Blotting, Western; Cell Line, Tumor; Cells, Cultured; Curcumin/chemistry; Drug Carriers/administration & dosage; Drug Carriers/therapeutic use; Female; Flow Cytometry; Lipopolysaccharides/toxicity; Mice; Mice, Inbred C57BL; Nanoparticles/administration & dosage; Shock, Septic/chemically induced; Shock, Septic/drug therapy

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Aromoterapia / Plantas_medicinales Main subject: Curcumin / Nanoparticles / Exosomes / Anti-Inflammatory Agents Language: En Journal: Mol Ther Year: 2010 Type: Article Affiliation country: United States

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