Tongxinluo reduces myocardial no-reflow and ischemia-reperfusion injury by stimulating the phosphorylation of eNOS via the PKA pathway.

Li, Xiang-Dong; Yang, Yue-Jin; Geng, Yong-Jian; Jin, Chen; Hu, Feng-Huan; Zhao, Jing-Lin; Zhang, Hai-Tao; Cheng, Yu-Tong; Qian, Hai-Yan; Wang, Lin-Lin; Zhang, Bao-Jie; Wu, Yi-Ling

Li, Xiang-Dong; Yang, Yue-Jin; Geng, Yong-Jian; Jin, Chen; Hu, Feng-Huan; Zhao, Jing-Lin; Zhang, Hai-Tao; Cheng, Yu-Tong; Qian, Hai-Yan; Wang, Lin-Lin; Zhang, Bao-Jie; Wu, Yi-Ling.

Affiliation

Li XD; Department of Cardiology, Fuwai Hospital and Cardiovascular Institute, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.

Am J Physiol Heart Circ Physiol ; 299(4): H1255-61, 2010 Oct.

Article in En | MEDLINE | ID: mdl-20693395

Subject(s)

Cyclic AMP-Dependent Protein Kinases/metabolism; Drugs, Chinese Herbal/therapeutic use; Myocardial Reperfusion Injury/prevention & control; Nitric Oxide Synthase Type III/metabolism; Signal Transduction/physiology; Animals; Creatine Kinase/blood; Cyclic AMP-Dependent Protein Kinases/antagonists & inhibitors; Dose-Response Relationship, Drug; Drugs, Chinese Herbal/pharmacology; Isoquinolines/pharmacology; Models, Animal; Myocardial Reperfusion Injury/metabolism; Phosphorylation; Protein Kinase Inhibitors/pharmacology; Signal Transduction/drug effects; Sulfonamides/pharmacology; Swine; Swine, Miniature

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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Therapeutic Methods and Therapies TCIM: Terapias_biologicas Main subject: Drugs, Chinese Herbal / Myocardial Reperfusion Injury / Signal Transduction / Cyclic AMP-Dependent Protein Kinases / Nitric Oxide Synthase Type III Language: En Journal: Am J Physiol Heart Circ Physiol Year: 2010 Type: Article Affiliation country: China

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