Probing the anticancer mechanism of prospective herbal drug Withaferin A on mammals: a case study on human and bovine proteasomes.

Grover, Abhinav; Shandilya, Ashutosh; Bisaria, Virendra S; Sundar, Durai

Grover, Abhinav; Shandilya, Ashutosh; Bisaria, Virendra S; Sundar, Durai.

Affiliation

Grover A; Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology (IIT) Delhi, Hauz Khas, New Delhi, India. abhinavgr@gmail.com

BMC Genomics ; 11 Suppl 4: S15, 2010 Dec 02.

Article in En | MEDLINE | ID: mdl-21143798

Subject(s)

Antineoplastic Agents/pharmacology; Plant Preparations/pharmacology; Proteasome Inhibitors; Withanolides/pharmacology; Animals; Antineoplastic Agents/metabolism; Antineoplastic Agents/therapeutic use; Apoptosis/drug effects; Cattle; Computational Biology/methods; Humans; Ligands; Models, Molecular; Plant Preparations/metabolism; Plant Preparations/therapeutic use; Proteasome Endopeptidase Complex/metabolism; Proteasome Endopeptidase Complex/physiology; Protein Binding; Signal Transduction/drug effects; Withanolides/chemistry; Withanolides/therapeutic use

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Full text: 1 Database: MEDLINE Main subject: Plant Preparations / Withanolides / Proteasome Inhibitors / Antineoplastic Agents Type of study: Prognostic_studies Language: En Journal: BMC Genomics Year: 2010 Type: Article Affiliation country: India

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