Determination of ligustilide in the brains of freely moving rats using microdialysis coupled with ultra performance liquid chromatography/mass spectrometry.

Guo, Jianming; Shang, Er-xin; Duan, Jin-ao; Tang, Yuping; Qian, Dawei

Guo, Jianming; Shang, Er-xin; Duan, Jin-ao; Tang, Yuping; Qian, Dawei.

Affiliation

Guo J; Jiangsu Key laboratory for TCM Formulae Research, Nanjing University of Chinese Medicine, Nanjing, PR China.

Fitoterapia ; 82(3): 441-5, 2011 Apr.

Article in En | MEDLINE | ID: mdl-21156197

Subject(s)

4-Butyrolactone/analogs & derivatives; Brain/metabolism; Ligusticum/chemistry; Plant Extracts/pharmacokinetics; 4-Butyrolactone/administration & dosage; 4-Butyrolactone/pharmacokinetics; Administration, Mucosal; Animals; Chromatography, High Pressure Liquid/methods; Male; Mass Spectrometry/methods; Microdialysis/methods; Nasal Mucosa; Plant Extracts/administration & dosage; Rats; Rats, Sprague-Dawley

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Full text: 1 Database: MEDLINE Main subject: Brain / 4-Butyrolactone / Plant Extracts / Ligusticum Language: En Journal: Fitoterapia Year: 2011 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Brain / 4-Butyrolactone / Plant Extracts / Ligusticum Language: En Journal: Fitoterapia Year: 2011 Type: Article