Isolinderanolide B, a butanolide extracted from the stems of Cinnamomum subavenium, inhibits proliferation of T24 human bladder cancer cells by blocking cell cycle progression and inducing apoptosis.

Shen, Kun-Hung; Lin, En-Shyh; Kuo, Po-Lin; Chen, Chung-Yi; Hsu, Ya-Ling

Shen, Kun-Hung; Lin, En-Shyh; Kuo, Po-Lin; Chen, Chung-Yi; Hsu, Ya-Ling.

Affiliation

Shen KH; Chi Mei Medical Center, Tainan, Taiwan.

Integr Cancer Ther ; 10(4): 350-8, 2011 Dec.

Article in En | MEDLINE | ID: mdl-21196431

Subject(s)

4-Butyrolactone/analogs & derivatives; Apoptosis/drug effects; Cell Proliferation/drug effects; Cinnamomum; Plant Extracts/pharmacology; Urinary Bladder Neoplasms/metabolism; 4-Butyrolactone/pharmacology; Caspase 8/metabolism; Cell Cycle Checkpoints/drug effects; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21/metabolism; Fas Ligand Protein/metabolism; Humans; Plant Stems; Tumor Suppressor Protein p53/metabolism; Urinary Bladder Neoplasms/pathology; fas Receptor/metabolism

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Full text: 1 Database: MEDLINE Main subject: Urinary Bladder Neoplasms / 4-Butyrolactone / Plant Extracts / Apoptosis / Cinnamomum / Cell Proliferation Language: En Journal: Integr Cancer Ther Year: 2011 Type: Article Affiliation country: Taiwan

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