Berberine as a promising safe anti-cancer agent - is there a role for mitochondria?

Diogo, Catia V; Machado, Nuno G; Barbosa, Inês A; Serafim, Teresa L; Burgeiro, Ana; Oliveira, Paulo J

Diogo, Catia V; Machado, Nuno G; Barbosa, Inês A; Serafim, Teresa L; Burgeiro, Ana; Oliveira, Paulo J.

Affiliation

Diogo CV; Center for Neuroscience and Cell Biology, Department of Life Sciences, University of Coimbra, Portugal.

Curr Drug Targets ; 12(6): 850-9, 2011 Jun.

Article in En | MEDLINE | ID: mdl-21269266

Subject(s)

Berberine/pharmacology; Mitochondria/drug effects; Neoplasms/drug therapy; Animals; Antineoplastic Agents, Phytogenic/adverse effects; Antineoplastic Agents, Phytogenic/isolation & purification; Antineoplastic Agents, Phytogenic/pharmacology; Berberidaceae/chemistry; Berberine/adverse effects; Berberine/isolation & purification; Drug Delivery Systems; Electron Transport Complex I/antagonists & inhibitors; Humans; Medicine, Traditional; Mitochondria/metabolism; Neoplasms/pathology

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Database: MEDLINE Therapeutic Methods and Therapies TCIM: Plantas_medicinales Main subject: Berberine / Mitochondria / Neoplasms Language: En Journal: Curr Drug Targets Year: 2011 Type: Article Affiliation country: Portugal

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