Alkaloids/therapeutic use; Alzheimer Disease/drug therapy; Amyloid beta-Peptides/metabolism; Cholinesterase Inhibitors/therapeutic use; Sesquiterpenes/therapeutic use; Signal Transduction/drug effects; Wnt Proteins/metabolism; beta Catenin/metabolism; Acetylcholinesterase/metabolism; Alzheimer Disease/genetics; Alzheimer Disease/metabolism; Alzheimer Disease/pathology; Amyloid beta-Protein Precursor/genetics; Analysis of Variance; Animals; Blood-Retinal Barrier/drug effects; Blood-Retinal Barrier/ultrastructure; Bromodeoxyuridine/metabolism; Cell Survival/drug effects; Cell Survival/ethics; Disease Models, Animal; Enzyme Inhibitors/pharmacology; Enzyme-Linked Immunosorbent Assay/methods; Gene Expression Regulation/drug effects; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal/methods; Microscopy, Electron, Scanning/methods; Mutation/genetics; Nerve Tissue Proteins/genetics; Nerve Tissue Proteins/metabolism; Neuroblastoma/pathology; Neuroblastoma/ultrastructure; Neurogenesis/drug effects; Olfactory Bulb/metabolism; Olfactory Bulb/ultrastructure; Presenilin-1/genetics; RNA, Messenger/metabolism; Transfection/methods; Wnt Proteins/genetics; beta Catenin/genetics