Studies on target tissue distribution of ginsenosides and epimedium flavonoids in rats after intravenous administration of Jiweiling freeze-dried powder.

Liu, Minyan; Wang, Hongtao; Zhao, Shaohua; Shi, Xiaowei; Zhang, Yongfeng; Xu, Honghui; Wang, Yufeng; Li, Xiangjun; Zhang, Lantong

Liu, Minyan; Wang, Hongtao; Zhao, Shaohua; Shi, Xiaowei; Zhang, Yongfeng; Xu, Honghui; Wang, Yufeng; Li, Xiangjun; Zhang, Lantong.

Affiliation

Liu M; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University, Shijiazhuang, 050017, China; Institute of Hebei Yiling Pharmaceutical Co., Ltd., Shijiazhuang, 050035, China.

Biomed Chromatogr ; 25(11): 1260-72, 2011 Nov.

Article in En | MEDLINE | ID: mdl-21337352

Subject(s)

Drugs, Chinese Herbal/pharmacokinetics; Epimedium/chemistry; Flavonoids/pharmacokinetics; Ginsenosides/pharmacokinetics; Administration, Intravenous; Animals; Chromatography, High Pressure Liquid/methods; Drugs, Chinese Herbal/administration & dosage; Drugs, Chinese Herbal/analysis; Flavonoids/analysis; Ginsenosides/analysis; Linear Models; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization/methods; Tissue Distribution

Key words

HPLC-ESI-MS/MS; Jiweiling freeze-dried powder; epimedium flavonoids; ginsenosides; target tissue distribution

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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Flavonoids / Drugs, Chinese Herbal / Epimedium / Ginsenosides Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Biomed Chromatogr Year: 2011 Type: Article Affiliation country: China

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