Coffees rich in chlorogenic acid or N-methylpyridinium induce chemopreventive phase II-enzymes via the Nrf2/ARE pathway in vitro and in vivo.

Boettler, Ute; Volz, Nadine; Pahlke, Gudrun; Teller, Nicole; Kotyczka, Christine; Somoza, Veronika; Stiebitz, Herbert; Bytof, Gerhard; Lantz, Ingo; Lang, Roman; Hofmann, Thomas; Marko, Doris

Boettler, Ute; Volz, Nadine; Pahlke, Gudrun; Teller, Nicole; Kotyczka, Christine; Somoza, Veronika; Stiebitz, Herbert; Bytof, Gerhard; Lantz, Ingo; Lang, Roman; Hofmann, Thomas; Marko, Doris.

Affiliation

Boettler U; University of Vienna, Department of Food Chemistry and Toxicology, Vienna, Austria.

Mol Nutr Food Res ; 55(5): 798-802, 2011 May.

Article in En | MEDLINE | ID: mdl-21448860

Subject(s)

Antioxidants/pharmacology; Chemoprevention; Chlorogenic Acid/pharmacology; Coffee/chemistry; NF-E2-Related Factor 2/physiology; Pyridinium Compounds/pharmacology; Response Elements/physiology; Enzyme Induction/drug effects; Glutamate-Cysteine Ligase/biosynthesis; HT29 Cells; Heme Oxygenase-1/biosynthesis; Humans; Reactive Oxygen Species/metabolism

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Full text: 1 Database: MEDLINE Main subject: Pyridinium Compounds / Chlorogenic Acid / Coffee / Chemoprevention / Response Elements / NF-E2-Related Factor 2 / Antioxidants Type of study: Prognostic_studies Language: En Journal: Mol Nutr Food Res Year: 2011 Type: Article Affiliation country: Austria

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