Characterization of the human QT interval: novel distribution-based assessment of the repolarization effects of moxifloxacin.

Holzgrefe, Henry H; Ferber, Georg; Morrison, Royce; Meyer, Olivier; Greiter-Wilke, Andrea; Singer, Thomas

Holzgrefe, Henry H; Ferber, Georg; Morrison, Royce; Meyer, Olivier; Greiter-Wilke, Andrea; Singer, Thomas.

Affiliation

Holzgrefe HH; Department of Toxicology, Charles River Laboratories, Reno, NV 89511, USA. Henry.Holzgrefe@crl.com

J Clin Pharmacol ; 52(8): 1222-39, 2012 Aug.

Article in En | MEDLINE | ID: mdl-21659628

Subject(s)

Aza Compounds/therapeutic use; Electrocardiography/drug effects; Heart Rate/drug effects; Long QT Syndrome/drug therapy; Long QT Syndrome/physiopathology; Quinolines/therapeutic use; Adult; Female; Fluoroquinolones; Heart Rate/physiology; Humans; Male; Middle Aged; Moxifloxacin; Young Adult

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Aromoterapia Main subject: Quinolines / Aza Compounds / Long QT Syndrome / Electrocardiography / Heart Rate Type of study: Clinical_trials / Guideline Language: En Journal: J Clin Pharmacol Year: 2012 Type: Article Affiliation country: United States

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