Lanthanum carbonate, like sevelamer-HCl, retards the progression of vascular calcification and atherosclerosis in uremic apolipoprotein E-deficient mice.

Nikolov, Igor G; Joki, Nobuhiko; Nguyen-Khoa, Thao; Guerrera, Ida Chiara; Maizel, Julien; Benchitrit, Joyce; Machado dos Reis, Luciene; Edelman, Aleksander; Lacour, Bernard; Jorgetti, Vanda; Drüeke, Tilman B; Massy, Ziad A

Nikolov, Igor G; Joki, Nobuhiko; Nguyen-Khoa, Thao; Guerrera, Ida Chiara; Maizel, Julien; Benchitrit, Joyce; Machado dos Reis, Luciene; Edelman, Aleksander; Lacour, Bernard; Jorgetti, Vanda; Drüeke, Tilman B; Massy, Ziad A.

Affiliation

Nikolov IG; Inserm ERI-12, UFR de Médecine/Pharmacie, University of Picardie, Amiens, France.

Nephrol Dial Transplant ; 27(2): 505-13, 2012 Feb.

Article in En | MEDLINE | ID: mdl-21705467

Subject(s)

Apolipoproteins E/deficiency; Atherosclerosis/prevention & control; Lanthanum/pharmacology; Polyamines/pharmacology; Renal Insufficiency, Chronic/drug therapy; Vascular Calcification/prevention & control; Analysis of Variance; Animals; Aorta/drug effects; Aorta/pathology; Atherosclerosis/blood; Blood Chemical Analysis; Bone Density/physiology; Collagen/analysis; Collagen/metabolism; Disease Models, Animal; Disease Progression; Female; Immunohistochemistry; Lanthanum/metabolism; Mice; Mice, Inbred Strains; Polyamines/metabolism; Random Allocation; Reference Values; Renal Insufficiency, Chronic/physiopathology; Sevelamer; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Uremia/drug therapy; Uremia/physiopathology

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Full text: 1 Database: MEDLINE Main subject: Apolipoproteins E / Polyamines / Renal Insufficiency, Chronic / Atherosclerosis / Vascular Calcification / Lanthanum Language: En Journal: Nephrol Dial Transplant Year: 2012 Type: Article Affiliation country: France

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